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Section: New Results

Axis 4: Proteomic signature of early death in heart failure patients

Participants : Guillemette Marot, Vincent Vandewalle.

Heart failure (HF) remains a main cause of mortality worldwide. Risk stratification of patients with systolic chronic HF is critical to identify those who may benefit from advanced HF therapies. The aim of this study is to identify plasmatic proteins that could predict the early death (within 3 years) of HF patients with reduced ejection fraction hospitalized in CHRU de Lille. In this framework, we have performed LASSO logistic regression to perform variable selection in order to select candidates protein to predict early death in HF patients. An article has been accepted in Scientific Reports [19].

This is a joint work with Marie Cuvelliez, Florence Pinet and Christophe Bauters from INSERM.