Team, Visitors, External Collaborators
Overall Objectives
Research Program
Application Domains
New Software and Platforms
New Results
Bilateral Contracts and Grants with Industry
Partnerships and Cooperations
XML PDF e-pub
PDF e-Pub

Section: New Software and Platforms

Totoro & Kotoura

Keywords: Bioinformatics - Graph algorithmics - Systems Biology

Functional Description: Both Totoro and Kotoura decipher the reaction changes during a metabolic transient state, using measurements of metabolic concentrations. These are called metabolic hyperstories. Totoro (for TOpological analysis of Transient metabOlic RespOnse) is based on a qualitative measurement of the concentrations in two steady-states to infer the reaction changes that lead to the observed differences in metabolite pools in both conditions. In the currently available release, a pre-processing and a post-processing steps are included. After the post-processing step, the solutions can be visualised using Dinghy ( Kotoura (for Kantitative analysis Of Transient metabOlic and regUlatory Response And control) infers quantitative changes of the reactions using information on measurement of the metabolite concentrations in two steady-states.