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## Section: New Results

### Protein sequence and structure aligner for SAMSON

Participants : Guillaume Pages, Sergei Grudinin.

Aligning sequences and structures of proteins is important to understand both the homologies and differences between them. We developed a SAMSON element for this purpose, that can perform both sequence and structure alignment. The sequence alignment is done thanks to the software MUSCLE [36]. The structural alignment is done by finding the transformation that minimize the RMSD between corresponding backbones atoms in both structures. We used the algorithm presented by Kearsley [47].

Figure 21. The protein aligner element