Overall Objectives
Research Program
Highlights of the Year
New Software and Platforms
New Results
Bilateral Contracts and Grants with Industry
Partnerships and Cooperations
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Section: New Software and Platforms


Keywords: Bioinformatics - Statistics - Data visualization - Data modeling

WellInverter is a web application that implements linear inversion methods for the reconstruction of gene expression profiles from fluorescent or luminescent reporter gene data. As input, WellInverter reads the primary data file produced by a 96-well microplate reader, containing time-series measurements of the absorbance (optical density) as well as the fluorescence and luminescence intensities in each well (if available). Various modules exist to analyze the data, in particular for detecting outliers, subtracting background, estimating growth rates, promoter activities and protein concentrations, visualizing expression profiles, synchronizing replicate profiles, etc. The computational core of the web application consists of the Python library WellFARE .