Overall Objectives
Research Program
Application Domains
Highlights of the Year
New Software and Platforms
New Results
Bilateral Contracts and Grants with Industry
Partnerships and Cooperations
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Section: Overall Objectives


Understanding brain function and its alterations requires the integration of multiple levels of organization, operating at different spatial and temporal scales. The integration of such a large variety of data is now possible thanks to the recent emergence of large-scale multimodal datasets (e.g. Alzheimer's disease neuroimaging initiative [ADNI], gene expression atlases from the Allen Institute...). In this context, mathematical and computational approaches are becoming increasingly important because: i) they provide formalized, operational and flexible frameworks for integrating multiple processes and scales; ii) they allow automated processing and analysis of massive datasets. These approaches can then be used to find biomarkers of a disease, for genotype/phenotype correlations, or to characterize functional responses for instance.