Regliss – RNA locally optimal structures
Regliss is a tool that studies the energy landscape of a given RNA sequence by considering locally optimal structures. Locally optimal structures are thermodynamically stable structures that are maximal for inclusion: they cannot be extended without producing a conflict between base pairs in the secondary structure, or increasing the free energy. The tool generates all locally optimal structures in a given sequence. Moreover, Regliss can be used to explore the neighborhood of structures through an energy landscape graph.