Section: Overall Objectives

Overall Objectives

The purpose of Numed is to develop new numerical methods and tools to simulate and parametrize complex systems arising in biology and medecine. Numed focuses on two axes:

• numerical methods for complex systems with several time and spatial scales. In particular: numerical simulations in complex domains, stiff reaction diffusions equations, multifluids systems.

• parametrization of complex systems using nonlinear mixed effect methods and populationnal pharmacokinetic pharmacodynamics models.

Numed investigates two mains applications

• Stroke: models of brain stroke (ionic exchanges, inflammation, free radicals, ...)

• Cancer: local invasion, angiogenesis

and a few other subjects (prion models, FIV,...).