Section: Overall Objectives
Highlights of the year
In collaboration with the Génolevures Consortium and Washington University at St. Louis, MAGNOME completed a large-scale study of five complete yeast genomes from the implicated in various biotechnological applications. These species have been baptised “protoploid” because they are the best contemporary genomes representing the ancestral chomosome number for this phylogenetic branch. Nearly all of MAGNOME's core methodologies were brought on line for this study: genome annotation and analysis [18] , [15] , median and ancestral genome reconstruction [14] , [23] , data integration and web deployment [17] .
In collaboration with the Institute of Wine and Vine Science, MAGNOME improved understanding of the relation between genome variation and efficiency of cell factory microorganisms used in wine making.
Macha Nikolski (CR1 CNRS) of MAGNOME defended her HDR [11] .