Section: Other Grants and Activities

National initiatives

INRIA Large Collaborative Effort CARDIOSENSE3D

Participants : Hervé Delingette [ coordinator ] , Nicholas Ayache, Maxime Sermesant, Florence Billet, Tommaso Mansi, Adityo Prakosa, Nicolas Toussaint, Damien Lepiller, Jatin Relan, Jean-Marc Peyrat.

The action CARDIOSENSE3D is a 4-year large initiative action (2005-2009) on the topic of cardiac simulation. This action gathers the expertise of four INRIA research teams (Asclepios, Macs, Reo and Sisyphe) on this multi-disciplinary research topic. CardioSense3D has three main objectives:

1. to build a cardiac simulator that couples four different physiological phenomena,

2. to estimate patient specific parameters and state variables from observations (images, electrophysiology mappings) of the cardiac activity,

3. to build several applications to solve clinical problems related to the diagnosis or therapy of cardiac pathologies.

H. Delingette is in charge of the coordination of this action. More information can be found at the following web site http://www-sop.inria.fr/CardioSense3D/

ANR TechLog NeuroLOG

Participants : Xavier Pennec [ correspondant ] , Andrew Sweet, Pascal Girard, Grégoire Malandain.

The ARN TLOG NeuroLOG (2007-2010, neurolog.polytech.unice.fr ): project adresses software technologies for the integration of processes, data and knowledge in neurological medical imaging: management and access of partly structured data, heterogeneous and distributed in an open environment; access control and protection of private medical data; control of workflows implied in complex computing process on grid infrastructures; extraction and quantification of relevant parameters for three different pathologies: Multiple sclerosis, Brain Vascular Stroke and Brain tumors.

This is a multi-disciplinary project which associates partners in software technologies (I3S at Sophia- Antipolis, LRI in Orsay), databases (Business Objects, LaRIA, Visages at IRISA-Rennes) and medical imaging (Visages at IRISA-Rennes, Visioscopie, U594, IFR49, Asclepios at INRIA-Sophia).

INRIA Cooperative Research Initiative 3DMorphine

Participants : Xavier Pennec [ coordinator ] , Stanley Durrleman.

The aim of this two-year Collaborative Research Initiative is to devise, implement, validate and apply new mathematical and computational methods for the automated morphometric analysis of extant and extinct hominid cranial virtual endocasts. The particular interest of the Asclepios team is on the morphometric analysis of endocasts on different populations of subjects, including: modern humans, fossil pre-humans and humans (such as South African australopithecines, European Cro-Magnons and Neandertals), and the closest extant relatives of modern humans (i.e. chimps and bonobos).

The action is led by S. Prima from the Visages team at INRIA, Rennes, France. Other participants include the ICAR team at CNRS, Montpellier, France, the lab of paleoanthropology and anatomical imaging at the Université Paul Sabatier, Toulouse, France and the lab of general histology, neuroanatomy and neuropathology at the Université Libre de Bruxelles, Belgium.

Other Initiatives

The ATP CIRAD Meristem Grant and QUALICORE are described in our previous activity report.

Consulting for Industry

• Nicholas Ayache is scientific consultant for the company Mauna Kea Technologies (Paris).

• Grégoire Malandain is a member of the technical council of the company Dosisoft (Paris), a subsidiary from the Gustave Roussy Institute and the Curie Institute (Paris).

Collaboration with national hospitals

Here we provide a list of research centers in national hospitals with whom we collaborate in common research projects.

IRCAD, hôpitaux de Strasbourg

Pr. Marescaux and L. Soler : hepatic surgery simulation segmentation of abdominal structures from CT scan images and augmented reality for guidance in hepatic surgery [104] , [105] .

Centre anti-cancer Antoine Lacassagne, Hôpital Pasteur, Nice

Dr. Bondiau participates in our research on atlas registration for radiotherapy planning and on tumour growth simulation.

CHU de Nice, Hôpital Pasteur

We continue our collaboration with Dr. C. Lebrun-Frenay of the neurology department, and with Dr. Chanalet of the radiology department, within the framework of a study on the temporal evolution of MS lesion load [45] , [28] .

CHU de Nice, Hôpital L'Archet

We continue our collaboration with Pr. Dellamonica and Dr. Vassallo of the infectiology department on the study of cognitive impairment in HIV patients.

Collaboration with international hospitals

St Thomas' Hospital, King's College London, United Kingdom

Maxime Sermesant is a part-time lecturer in the Interdisciplinary Medical Imaging Group, Division of Imaging Sciences, St Thomas' Hospital, King's College London. The XMR facility within this hospital is a unique possibility to validate and exploit the cardiovascular modelling work.