Keywords : genetic network qualitative modelling (genetic network, qualitative modelling).
Genetic Network Analyzer (GNA)
Participants : Grégory Batt, Bruno Besson, Estelle Dumas, Hidde de Jong [ Correspondent ] , Pedro Monteiro, Michel Page, Delphine Ropers.
Genetic Network Analyzer (GNA) is the implementation of a method for the qualitative modelling and simulation of genetic regulatory networks developed in the HELIX project. The input of GNA consists of a model of the regulatory network in the form of a system of piecewise-linear differential equations, supplemented by inequality constraints on the parameters and initial conditions. From this information, GNA generates a state transition graph summarising the qualitative dynamics of the system. GNA is currently distributed by the company Genostar, but remains freely available for academic research purposes. For more information, see http://www-helix.inrialpes.fr/gna .